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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC6
All Species:
3.33
Human Site:
S878
Identified Species:
6.67
UniProt:
O95255
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95255
NP_001162.4
1503
164906
S878
T
K
D
P
R
G
T
S
A
G
R
R
P
E
L
Chimpanzee
Pan troglodytes
XP_001145351
1247
137800
Q670
L
M
E
A
D
K
A
Q
T
G
Q
V
K
L
S
Rhesus Macaque
Macaca mulatta
XP_001109862
1347
147568
K770
L
A
R
A
V
Y
R
K
A
A
V
Y
L
L
D
Dog
Lupus familis
XP_547113
1504
165780
A879
A
E
D
P
R
G
P
A
G
S
E
Q
P
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S7
1498
164770
P871
S
D
D
L
G
G
F
P
G
G
G
R
P
T
C
Rat
Rattus norvegicus
O88269
1502
164977
S876
S
D
D
L
G
G
F
S
G
G
G
T
P
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517193
1537
172363
K901
S
P
A
V
K
E
V
K
P
M
E
N
G
V
L
Chicken
Gallus gallus
Q5F364
1525
170953
N896
V
E
N
G
V
L
V
N
D
A
T
G
K
L
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341895
1518
169232
N889
V
P
R
K
G
L
E
N
G
G
P
A
A
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
M713
G
L
V
A
F
L
V
M
L
S
S
S
V
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LZJ5
1539
172119
R899
S
I
S
I
E
S
P
R
Q
P
K
S
P
K
V
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
S878
E
S
S
V
R
E
S
S
I
P
V
E
G
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.6
84.9
79.5
N.A.
78.5
78.4
N.A.
45
45.3
N.A.
45.9
N.A.
28.2
N.A.
N.A.
N.A.
Protein Similarity:
100
55.6
86.8
87.3
N.A.
85.8
86
N.A.
63.5
63.2
N.A.
64.1
N.A.
46.9
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
33.3
N.A.
33.3
33.3
N.A.
6.6
0
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
6.6
53.3
N.A.
40
40
N.A.
20
26.6
N.A.
20
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
52.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
25
0
0
9
9
17
17
0
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
17
34
0
9
0
0
0
9
0
0
0
0
0
9
% D
% Glu:
9
17
9
0
9
17
9
0
0
0
17
9
0
17
0
% E
% Phe:
0
0
0
0
9
0
17
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
25
34
0
0
34
42
17
9
17
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
0
9
9
9
0
17
0
0
9
0
17
9
0
% K
% Leu:
17
9
0
17
0
25
0
0
9
0
0
0
9
42
34
% L
% Met:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
17
0
0
0
9
0
0
0
% N
% Pro:
0
17
0
17
0
0
17
9
9
17
9
0
42
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
9
9
0
0
0
% Q
% Arg:
0
0
17
0
25
0
9
9
0
0
9
17
0
0
9
% R
% Ser:
34
9
17
0
0
9
9
25
0
17
9
17
0
0
9
% S
% Thr:
9
0
0
0
0
0
9
0
9
0
9
9
0
17
0
% T
% Val:
17
0
9
17
17
0
25
0
0
0
17
9
9
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _